产品货号:
Z23442
中文名称:
p38 MAPK/MAPK14抗体
英文名称:
Anti-p38 MAPK/MAPK14 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-p38 MAPK/MAPK14 Antibody |
指标别名 | CSAID binding protein;CSBP;CSBP1;CSBP2;CSPB1;EXIP;MAP kinase 14;MAP kinase MXI2;MAP kinase p38 alpha;MAPK 14;MAPK14;MAX interacting protein 2;Mxi2;p38;p38ALPHA;PRKM14;PRKM15;RK;SAPK2A |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB |
基因名称 | MAPK14 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Synthesized peptide derived from human p38 around the non-phosphorylation site of Y323. |
计算分子量 | 41KD |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | Immunogen affinity purified |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | Mitogen-activated protein kinase 14,also called p38-α,is an enzyme that in humans is encoded by the MAPK14 gene.The protein encoded by this gene is a member of the MAP kinase family.MAP kinases act as an integration point for multiple biochemical signals,and are involved in a wide variety of cellular processes such as proliferation,differentiation,transcription regulation and development.This kinase is activated by various environmental stresses and proinflammatory cytokines.The activation requires its phosphorylation by MAP kinase kinases (MKKs),or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase.The substrates of this kinase include transcription regulator ATF2,MEF2C,and MAX,cell cycle regulator CDC25B,and tumor suppressor p53,which suggest the roles of this kinase in stress related transcription and cell cycle regulation,as well as in genotoxic stress response.Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
Uniprot ID | Q16539 |
基因名全称 | Mitogen-activated protein kinase 14 |
推荐稀释比 | WB,1:500~1:2000 |
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